Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdkn1a  cyclin dependent kinase inhibitor 1A   (Synonyms: CAP20, CDKI, Cdkn1, CIP1, mda6, P21, p21Cip1, p21WAF, p21, SDI1, Waf1)
Results	Reference
1	J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32
1*	J:265803 Da Silva-Alverez S, Lamas-Gonzalez O, Ferreiros A, Gonzalez P, Gomez M, Garcia-Caballero T, Gonzalez Barcia M, Garcia-Gonzalez MA, Collado M, Pkd2 deletion during embryo development does not alter mesonephric programmed cell senescence. Int J Dev Biol. 2018;62(9-10):637-640
1	J:86042 Ito Y, Yeo JY, Chytil A, Han J, Bringas P Jr, Nakajima A, Shuler CF, Moses HL, Chai Y, Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development. 2003 Nov;130(21):5269-80
1	J:194043 Iwata J, Suzuki A, Pelikan RC, Ho TV, Sanchez-Lara PA, Urata M, Dixon MJ, Chai Y, Smad4-Irf6 genetic interaction and TGFbeta-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development. 2013 Mar;140(6):1220-30
1	J:337812 Kim EJ, Kim HY, Li L, Tang Q, Kim KH, Ohshima H, Jung HS, Cuspal Shape Alterations by Bmp4 Directing Cell Proliferation and Apoptosis. J Dent Res. 2023 Jul;102(7):825-834
1	J:175828 Komatsu Y, Kaartinen V, Mishina Y, Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry. Development. 2011 Sep;138(18):3915-20
1*	J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68
1	J:331419 Labbe P, Munoz Goyette V, Thorin-Trescases N, Villeneuve L, Desanlis I, Delwarde C, Shi YF, Martel C, Yu C, Alikashani A, Mamarbachi M, Lesage F, Mathieu S, Tardif JC, Mathieu P, Kmita M, Thorin E, Angiopoietin-like 2 is essential to aortic valve development in mice. Commun Biol. 2022 Nov 21;5(1):1277
1	J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18
1	J:240835 Li CY, Hu J, Lu H, Lan J, Du W, Galicia N, Klein OD, alphaE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development. Nat Commun. 2016 Jul 13;7:12133
1*	J:278880 Li Y, Zhao H, Huang X, Tang J, Zhang S, Li Y, Liu X, He L, Ju Z, Lui KO, Zhou B, Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth. Cell Res. 2018 Jul;28(7):775-778
1	J:331948 Liu Z, Chen T, Bai D, Tian W, Chen Y, Smad7 Regulates Dental Epithelial Proliferation during Tooth Development. J Dent Res. 2019 Nov;98(12):1376-1385
1	J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189
1	J:306259 Luo W, Garcia-Gonzalez I, Fernandez-Chacon M, Casquero-Garcia V, Sanchez-Munoz MS, Muhleder S, Garcia-Ortega L, Andrade J, Potente M, Benedito R, Arterialization requires the timely suppression of cell growth. Nature. 2021 Jan;589(7842):437-441
1	J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819
1*	J:182715 Monahan P, Himes AD, Parfieniuk A, Raetzman LT, p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis. Mech Dev. 2012 Jan-Feb;128(11-12):640-52
1	J:205283 Munoz-Espin D, Canamero M, Maraver A, Gomez-Lopez G, Contreras J, Murillo-Cuesta S, Rodriguez-Baeza A, Varela-Nieto I, Ruberte J, Collado M, Serrano M, Programmed cell senescence during mammalian embryonic development. Cell. 2013 Nov 21;155(5):1104-18
1	J:109091 Nguyen L, Besson A, Heng JI, Schuurmans C, Teboul L, Parras C, Philpott A, Roberts JM, Guillemot F, p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev. 2006 Jun 1;20(11):1511-24
1*	J:342123 Sterling NA, Terry BK, McDonnell JM, Kim S, P53 independent pathogenic mechanisms contribute to BubR1 microcephaly. Front Cell Dev Biol. 2023;11:1282182
1*	J:170048 Vasey DB, Wolf CR, Brown K, Whitelaw CB, Spatial p21 expression profile in the mid-term mouse embryo. Transgenic Res. 2011 Feb;20(1):23-8
1	J:178707 Wang SK, Komatsu Y, Mishina Y, Potential contribution of neural crest cells to dental enamel formation. Biochem Biophys Res Commun. 2011 Nov 11;415(1):114-9
1	J:124023 Wu G, Glickstein S, Liu W, Fujita T, Li W, Yang Q, Duvoisin R, Wan Y, The anaphase-promoting complex coordinates initiation of lens differentiation. Mol Biol Cell. 2007 Mar;18(3):1018-29